May 17, 2026: The NIH Pragmatic Trials Collaboratory hosted a preconference workshop, "Innovations in Embedded Pragmatic Clinical Trials,” at the 47th Annual Meeting of the Society for Clinical Trials in Phoenix. This training workshop introduces opportunities for embedded research along with strategies for conducting innovative ePCTs that provide real-world evidence necessary to inform improvements in healthcare.
Agenda and Slides
Welcome
Emily O'Brien, PhD
Session 1: Opportunities for Embedded Pragmatic Clinical Trials (ePCTs)
Wendy Weber, ND, PhD, MPH
Session 2: Engaging and Aligning With Partners
Emily O'Brien, PhD
Session 3: ePCT Design
Patrick Heagerty, PhD
Session 4: Innovative Methods in ePCTs
Angelo Volandes, MD, MPH
Session 5: Overview of NIH Collaboratory Trials
*This presentation contains case studies
Session 6: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trial PIs
Moderators: Emily O'Brien, PhD; Nana Martinson, MPH
Panel: Sebastian Tong, MD, MPH; Michael Ho, MD, PhD
Closing Remarks
Emily O'Brien, PhD; Wendy Weber, ND, PhD, MPH
Case Studies
Examples from NIH Collaboratory Trials:
- Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain (AIM-CP) (Sebastian Tong, MD, MPH)
- Using Artificially Intelligent Text Messaging Technology to Improve American Heart Association’s Life’s Essential 8 Health Behaviors (Chat 4 Heart Health) (Michael Ho, MD, PhD)