July 16, 2021: Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials? (David Chambers, DPhil; Amanda Midboe, PhD; Anne Trontell, MD, MPH)

Posted on by terren.green@duke.edu

Speakers

Panel:
Amanda Midboe, PhD
Center for Innovation to Implementation
U.S. Department of Veterans Affairs
Chair of the Implementation Science Work Group for the NIH-DOD-VA Pain Management Collaboratory

Anne Trontell, MD, MPH
Associate Director
Clinical Effectiveness and Decision Science Program
Patient-Centered Outcomes Research Institute (PCORI)

Guest Moderator:
David Chambers, DPhil
Deputy Director for Implementation Science
Office of the Director in the Division of Cancer Control and Population Sciences (DCCPS)
National Cancer Institute (NCI)
National Institutes of Health (NIH)

Topic

Inclusion of Diverse Participants in Pragmatic Clinical Trials: Maximizing Diversity in PCTs – What Can We Learn From Implementation Trials?

Keywords

Dissemination research; Implementation research; Participant engagement; Participant diversity; Health equity; PCORI; Ci2i

Key Points

  • The study of methods to best implement and disseminate interventions in diverse groups is crucial to the ultimate goal of benefiting population health.

  • Patient-centered outcomes are important measures to determine the total effectiveness of any health intervention.

  • By engaging the community in which research takes place and treating patients as partners in the development of implementation strategies, we increase diverse participation and improve patient retention.

  • Targeted recruitment strategies that leverage administrative data increase diverse study participation.

  • Outreach materials and methods that are tailored and adapted to the local culture and colloquial language are effective in engaging diverse populations.

Discussion Themes

Are there any ethical issues raised when underserved populations receive monetary incentives to participate in research trials?

What are the challenges of identifying diverse potential participants from the medical record or administrative data?

Do efforts to increase diversity in the study team improve the engagement and retention of a diverse study population?

Read more about methods to increase diversity in implementation trials at the Patient-Centered Outcomes Research Institute (PCORI) and the Center for Innovation to Implementation (Ci2i).

Tags

#pctGR, @Collaboratory1