Welcome to the NIH Collaboratory’s Rethinking Clinical Trials: A Living Textbook of Pragmatic Clinical Trials! The Living Textbook is designed to provide information on how to understand, design, conduct, analyze & disseminate pragmatic clinical trials (PCTs).
Topic Chapters provide detailed, textbook-like information on various aspects of pragmatic clinical trials, complete with citations and links to resources.
Introduction • Conflict of Interest • Informed Consent • Patient-Reported Outcomes • Regulatory Issues • Learning Healthcare Systems • EHR Phenotyping
Tools for Research encompasses practical guidance and "toolkits" for conducting different aspects of pragmatic clinical research.
Electronic Phenotyping • Biostatistical Guidances • Data Quality • Computer-Adaptive Testing • Patient-Reported Outcomes White Papers • Writing for Clinical Research • Intro to Pragmatic Clinical Trials
The Living Textbook Blog offers news and updates related to pragmatic clinical research, as well as bulletins about new content available on Rethinking Clinical Trials and the NIH Collaboratory Knowledge Repository.
Blog Front Page • RSS Feed • Knowledge Repository • Collaboratory Grand Rounds
Originally published on January 3, 2014.
Updated April 13, 2015.
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