HealthCore Data Description

HealthCore Data Description

NIH Collaboratory Distributed Research Network

​Years of data available 2006-2017
Total enrollees in research database: All years 65,189,820
​Total enrollees in research database: Most recent year 22,037,465
​Age distribution (%): Most recent year
​0-18 years 21.41
​19-44 years 36.82
​45-64 years 31.42
​65+ 10.34
​Data models available ​Sentinel Common Data Model (CDM)

Observational Medical Outcomes Partnership (OMOP) CDM


​Health plan/health system description HealthCore, Inc. (established 1996) is an independently operating, wholly owned subsidiary of Anthem, Inc.  Anthem is among the largest health benefits company in terms of medical enrollment in the United States. HealthCore combines clinical and scientific expertise with access to a robust data environment, to generate new knowledge that assists health plans, federal and state governments, and the pharmaceutical industry to make better health care decisions for the people they serve.

By leveraging HealthCore’s unique research environment, which comprises of a longitudinally integrated medical and pharmacy claims and electronic laboratory result database, with the ability to enrich the data with inpatient and outpatient medical records, national vital records for a portion of these lives, and access to a provider network with deep local market penetration.

The HealthCore Integrated Research Database (HIRD) is owned and operated by HealthCore and includes automated computerized claims data and enrollment information from 2006 to September 2017 for approximately 65 million lives with at least medical enrollment, and nearly 48 million lives with medical and pharmacy enrollment information from 14 Blue Cross and/or Blue Shield (BCBS) licensed plans. The HIRD also contains diagnostic laboratory testing results from two large national laboratories for Anthem-affiliated health plan members receiving outpatient laboratory services from over 22 million lives.

​Collaboration requirements and additional information ​HealthCore policy requires that all studies that involve the disclosure of any Protected Health Information (PHI) or are federally funded go through the IRB approval process prior to beginning the study. The collaborators are required to complete and sign confidentiality agreement and data sharing agreement, and only use data following IRB-approved study protocols.
​Research capabilities ​HealthCore specializes in health economics and outcomes research, comparative effectiveness research, epidemiologic research, and drug, vaccine, and biologic safety monitoring and surveillance for both public (federal or local) organizations, private pharmaceutical and device manufacturers, and academia. In addition to the expertise of the study team, HealthCore provides one of the largest commercial insurance research data environments in the United States.


NIH Collaboratory Distributed Research Network (DRN): HealthCore Data Description. In: Rethinking Clinical Trials: A Living Textbook of Pragmatic Clinical Trials. Bethesda, MD: NIH Health Care Systems Research Collaboratory. Available at: Updated April 3, 2018.