April 27, 2018: Collaboratory Investigators Pen Editorial Calling for Pragmatic Trials of Nonpharmacologic Dementia Interventions

NIH Collaboratory investigators Dr. Susan Mitchell and Dr. Vincent Mor coauthored an editorial for an upcoming issue of JAMDA highlighting the need for pragmatic trials of nonpharmacologic interventions in Alzheimer disease and related dementias. The editorial summarizes conclusions from a recent workshop at the National Institute on Aging (NIA), where experts discussed the state of the science for pragmatic trials to improve dementia care.

The goals of the NIA workshop were (1) to identify criteria for determining the readiness of dementia interventions for pragmatic trials, and (2) to describe the research infrastructure needed to support such trials.

Read the full editorial: Identifying and Supporting Nonpharmacological Dementia Interventions Ready for Pragmatic Trials: Results From an Expert Workshop

Drs. Mitchell and Mor are co-principal investigators of the NIH Collaboratory’s Pragmatic Trial of Video Education in Nursing Homes (PROVEN), which is evaluating the effectiveness of advance care planning video tools in nursing home settings. The editorial mentions that a supportive infrastructure for pragmatic research in dementia could be modeled after the NIH Collaboratory’s Coordinating Center, including Core Working Groups “focused on building investigator capacity, supporting pragmatic trial design, and maintaining the resource and knowledge base.”

Full citation: Baier RR, Mitchell SL, Jutkowitz E, Mor V. Identifying and supporting nonpharmacological dementia interventions ready for pragmatic trials: results from an expert workshop. J Am Med Dir Assoc. doi: 10.1016/j.jamda.2018.02.011.