MURDOCK Study Data Description for NIH Collaboratory Distributed Research Network
|Years of Data Available||2008-Current|
|Total enrollees in registry: All years||12,258|
|Target enrollment||No upper limit|
|Age distribution (%): Most recent year|
|Data models available|
|Informatics for Integrating Biology & the Bedside (i2b2) CDM||Yes|
|Health Plan/Health System Description||The MURDOCK Study Community Registry and Biorepository is a ground-breaking, longitudinal community-based, disease-agnostic registry and biospecimen repository established in 2008 in Kannapolis/Cabarrus County, North Carolina. The catchment region – a 20-zip code area – from which the MURDOCK Study cohort has been recruited includes >201,000 people who represent many groups under-represented in biomedical research, e.g. African Americans, Hispanics, economically disadvantaged, and women. This rich resource provides a substrate from which population health research studies can be executed, thereby striving to understand health and defeat some of today’s leading causes of illness and death.|
|Collaboration requirements and additional information||
All requests to collaborate with the Translational Population Health Research Program of the Duke Clinical & Translational Science Institute in order to gain access to samples and data of the MURDOCK Study cohort are required to be submitted via the study’s online Proposal Concept Form (found here). The MURDOCK Study Leadership team reviews these submissions on a rolling basis. Once approved and funded by external sources, any new data generated from the analysis of MURDOCK Study biospecimens or associated MURDOCK Study data must be returned to the MURDOCK Integrated Data Repository (MIDR).
Authorship on publications that result from collaborating with the MURDOCK Study are expected to follow rules of significant contribution and adhere to authorship standards described in the International Committee of Medical Journal Editors’ Uniform Requirements for Manuscripts Submitted to Medical Journals. All publications resulting from the use of MURDOCK Study data sets should acknowledge the MURDOCK Study and Duke University’s CTSA grant and must be submitted to PubMed Central.
The MURDOCK Study offers investigators and collaborators a comprehensive set of research assets and capabilities to undertake biomarker exploration and discovery using well-annotated, banked biospecimens and recruitment into prospective clinical trials, epidemiologic and health services research, and validation studies. The MURDOCK Study cohort also offers a highly valuable “point in time” look at a diverse population and study controls, defined as needed.
The infrastructure that was created to support the MURDOCK Study now includes 5,000 square feet of office and clinical examination space and laboratory with -80 freezers where a skilled staff of 25 FTEs are available to support a breadth of project needs ranging from project management, clinical coordination, community outreach and recruitment, regulatory oversight, data management, communications and marketing, translational services, and business development.